Tissue Engineering the Vascular Tree
نویسندگان
چکیده
منابع مشابه
Overview on Vascular Tissue Engineering: Progress and Challenges
Today, vascular diseases such as atherosclerosis are one of the leading causes of death in the world and the prevalence of it in older societies is rising. The current treatments for repair of cardiovascular function include organ transplantation, surgical reconstruction, mechanical or artificial devices, or the use of metabolic products. Although these methods are commonly used, they did not g...
متن کاملVascular tissue engineering : designer arteries.
The fields of vascular biology and vascular medicine are so intertwined that advances in one predict, explain, or are required for progress in the other. Bypass grafting, which once served as a “bailout” procedure,1,2 is now performed more than 600 000 times annually in the United States. In major part, this increase can be attributed to a surge in understanding of the vascular response to inju...
متن کاملTissue engineering of vascular grafts
Tissue engineering of vascular grafts 187 1 3 Summary Background There is a considerable clinical need for a sufficient prosthetic small-diameter substitute which can compete with autologous vessels. Currently used synthetic materials have a poor performance due to high thrombogeneicity and development of intimal hyperplasia. Tissue engineering is an interesting alternative approach for vascula...
متن کاملPulmonary tissue engineering using dual-compartment polymer scaffolds with integrated vascular tree.
OBJECTIVES The persistent shortage of donor organs for lung transplantation illustrates the need for new strategies in organ replacement therapy. Pulmonary tissue engineering aims at developing viable hybrid tissue for patients with chronic respiratory failure. METHODS Dual-chamber polymer constructs that mimic the characteristics of the pulmonary air-blood interface were fabricated by microf...
متن کاملTransmural flow bioreactor for vascular tissue engineering.
Nutrient transport limitation remains a fundamental issue for in vitro culture of engineered tissues. In this study, perfusion bioreactor configurations were investigated to provide uniform delivery of oxygen to media equivalents (MEs) being developed as the basis for tissue-engineered arteries. Bioreactor configurations were developed to evaluate oxygen delivery associated with complete transm...
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ژورنال
عنوان ژورنال: Tissue Engineering Part B: Reviews
سال: 2017
ISSN: 1937-3368,1937-3376
DOI: 10.1089/ten.teb.2017.0010